KPV is a naturally occurring tripeptide composed of lysine, proline, and valine. It represents the C-terminal sequence of alpha-melanocyte-stimulating hormone (α-MSH) and has attracted scientific interest for its role in inflammatory signaling, immune-related pathways, and peptide-mediated cellular communication. Experimental research has investigated KPV across cellular and preclinical models involving NF-κB signaling, cytokine activity, epithelial biology, and inflammatory responses.
Reviora Labs KPV 10mg is supplied as a lyophilized peptide powder containing 10mg of KPV per vial. It is intended for research and analytical applications involving peptide pharmacology, inflammatory signaling pathways, epithelial biology, and immune-related cellular processes.
Research Overview
KPV has generated particular interest as a biologically active fragment of α-MSH. Unlike the full-length melanocortin peptide, experimental findings suggest that KPV may influence inflammatory signaling through mechanisms that are not solely dependent on classical melanocortin receptor activity. Research has investigated pathways involving cytokine signaling, NF-κB activation, and cellular responses to inflammatory stimuli.
Studies using cell and animal models have examined KPV in relation to NF-κB-mediated signaling and the regulation of inflammatory mediators. Additional research has explored the uptake of KPV through the PepT1 peptide transporter in intestinal and epithelial cells, making peptide transport and epithelial signaling important areas of ongoing investigation.
KPV & Inflammatory Signaling Research
One of the primary areas of scientific interest surrounding KPV is its interaction with inflammatory signaling pathways. Experimental research has reported effects on NF-κB activity, cytokine-related signaling, and chemokine expression in specific cellular and preclinical models.
These findings continue to support interest in KPV as a research compound for studying how small peptide fragments may influence cellular responses to inflammatory stimuli. However, the underlying mechanisms and biological activity remain active areas of investigation.
KPV & Epithelial Research
KPV has also been studied in epithelial models, particularly in relation to peptide transport and cellular signaling. Research involving intestinal epithelial cells has investigated PepT1-mediated uptake and downstream effects on inflammatory pathways.
This makes KPV a compound of interest for research involving epithelial biology, peptide transport mechanisms, and interactions between cellular signaling and inflammatory responses.
Key Research Areas
- Tripeptide research
- Inflammatory signaling pathways
- NF-κB research
- Cytokine and chemokine signaling
- Immune-related cellular pathways
- Epithelial biology
- Peptide transport research
- PepT1-mediated uptake
- α-MSH-derived peptide research
- Peptide pharmacology
Product Specifications
Brand: Reviora Labs
Active Ingredient: KPV
Full Name: Lys-Pro-Val
Peptide Sequence: Lys-Pro-Val (KPV)
Concentration: 10mg per vial
Appearance: Lyophilized Powder
Product Category: Tripeptide Research
Storage & Handling
Store under appropriate refrigerated conditions and protect the product from excessive heat, light, and moisture. Follow suitable laboratory storage and handling procedures to help maintain product integrity and stability.
Research Use Notice
This product is intended for research and laboratory purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and is not intended for human or veterinary use.
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